severe pain, mental suffering or unhappiness
"It pains me to see my children not being taught well in school"
The beauty of the scene appeased the anguish of his heart.
出自： A. J. Cronin
When I went to see her after Rickie's death she was in anguish.
出自： R. Lehmann
My head was heavy with pain and any movement brought twinges of anguish.
出自： I. Murdoch