Under the optimized conditions, the cycloadduct wasobtained in good yield (76%) with excellent enantioseletivity (93%ee) in thepresence of 5 mol% chiral Ti complex.

• 在优化的反应条件下,采用 5 mol%25的手性钛席夫碱络合物催化 Brassard二烯与苯甲醛的不对称 Hetero-Diels-Alder 反应,产率达 76%25,对映选择性达 93%25ee。