To further evaluate this approach and its safety, Rosenthal created mice genetically engineered to overproduce IGF-I throughout their skeletal muscle.

• 为了进一步评估这种方法和其安全性，罗森塔尔培育了在所有骨骼肌内IGF-1表现过量的遗传工程改造小鼠，结果令人振奋。