To explore the variation law of serum estradiol (E_2) level in patients with gallstone (GS) and gallbladder carcinoma (GBC).

• 本文探讨胆囊结石及胆囊癌患者血清E_2水平的变化规律，研究雌性激素在胆囊成石及胆囊癌变过程中的作用。