The role of As 4S 4 was stronger that of than As 2S 3. Conclusion Down regulating TF expression and PCA of MR2 cells by arsenic sulfide may be one of the mechanims of its improvement on DIC related hemorrhage in APL patients.

• 结论 下调MR2细胞组织因子的表达并降低其促凝活性可能是硫化砷改善急性早幼粒细胞白血病 (APL)患者弥散性血管内凝血 (DIC)早期出血症状的主要机制之一