The murine pulmonary fibrosis model induced by one-off injection of bleomycin (BLM) was stable and manageable, indicating BLM induced pulmonary fibrosis model is still a classic way.

• 结果显示：1、昆明小鼠气管内一次性滴入博莱霉素复制的肺纤维化动物模型具有良好的稳定性和可操作性，提示应用博莱霉素复制肺纤维化模型仍不失为一种经典的方法。