The effects of sodium metabisulfite (SMB), as the provider of SO_2 derivatives, on voltage-dependent sodium and potassium channels were examined in rat hippocampal CA1 neurons.

• 在时间动力学方面，SMB增大钠电流的激活和失活时间常数。 对于电压依赖性钾通道，SMB剂量依赖性地增大大鼠海马CA1区神经元的瞬间外向钾电流(I_A)和延迟整流钾电流(I_K)。