The decreased expressions of adiponectin and resistin might play an important role in weight gain,hyperglycemia,abnormal lipid metabolism and insulin resistance in rats fed with high fat.

• 抵抗素和脂联素水平的降低是高脂饲养大鼠体重增加、血糖升高、脂质代谢紊乱和胰岛素抵抗的重要原因。