The decrease of TRH and the steady of active TRH receptor may protect the brain tissue and repress multiple organ dysfunction syndrome(MODS) in the early stage of endotoxemia.

• 内毒素血症早期脑内TRH减少及有活性TRH受体含量稳定可能与机体对脑组织的保护作用及遏制多器官功能障碍综合征进展有关。