Sickle cell disease is a group of inherited disorders of the hemoglobin molecule which, when exposed to various conditions (to be discussed later this week), cause the red blood cell hemoglobin to polymerize and distort the cell into a sickle shape.

• 镰状细胞病是一种遗传性血红蛋白分子功能紊乱疾患，当血红蛋白分子暴露在各种环境中（以后将讨论），红细胞血红蛋白发生聚合，扭曲变形成镰状。