Sham-operation group ?n=30? The operation on rats was similar to that of the model group? except that the left renal artery did not settle the silver clip. Fifteen rats were killed at the end of the 4th and 12th week? respectively after anesthesia.

• 假手术组(n=30):手术操作除左肾动脉不安置银夹外,余同模型组,于术后4周末及12周末各麻醉处死15只。