Results The amount of HPMC and lactose had significant effects on the release of allopurinol.The release behavior of the tablets followed the zero order equation.

• 结果羟丙基甲基纤维素(HPMC)和乳糖的用量对释药有显著性影响,别嘌醇缓释骨架片的体外释药行为符合零级释放模型。