Our results further demonstrate that expression of PML in GBC-SD cells has little effect on cell cycle distribution.

• DNA片段分析结果显示Ad-PML感染后GBC-SD细胞出现DNA降解带，TUNEL检测发现Ad-PML感染后凋亡细胞数量明显增加，但PML对胆囊癌细胞株GBC-SD的细胞周期无明显影响。