One of the efforts to enhance the biological activity of oligonucleotides as inhibitors of gene expression has been made by improvement of their stability to nuclease digestion.

• 为提高寡核苷酸作为基因表达抑制剂的生物活性, 人们所做的努力之一是增加它们的稳定性, 以耐受核酸酶的降解。