Objective:To study chemosensitivity and anticancer activity of Cisplatin(CDDP) loaded polylactic acid-polyethylene glycol nanoparticles(CDDP-PLA-PEG-NP) against oral squamous carcinoma cell lines Tca8113(tongue carcinoma) and BcaCD885(buccal carcinoma).

• 目的:观察口腔鳞癌细胞系(Tca8113和BcaCD885)对口腔癌靶向顺铂聚乳酸聚乙二醇纳米粒(CDDP-PLA-PEG-NP,或称隐形聚乳酸纳米)的敏感性,并与顺铂(CDDP)对Tca8113和BcaCD885的抗癌活性进行对比观察。