Objective To study the changes in plasma endothelin(ET) of dogs w hose bile-ducts were ligated and investigate the role of ET in impaired renal f unction of dogs with obstructive jaundice.

• 目的了解梗阻性黄疸动物体内血浆内皮素(ET)含量变化情况，探讨ET在梗阻性黄疸时肾脏损害机制中的作用。