OBJECTIVE: To observe the effect of aldose reductase inhibitor(ARI) on the activity of corneal aldose reductase (AR) and Na+-K+ATPase , and on corneal lesions in early diabetic rats and to investigate the protective mechanism.

• 目的:观察醛糖还原酶抑制剂(ARI)对糖尿病早期大鼠角膜组织中醛糖还原酶活性(AR)、钠-钾-ATP酶活性(Na+-K+ATPase)和角膜病变的影响,并探讨其防治效应及其机制。