Moclobelide was synthesized from ethanolamine by nucleophilic substitution and Schotten-Baumann reaction, followed by condensation with anoverall yield of 71.2%.

• 摘要以乙醇胺为起始原料，经亲核取代、肖特-鲍曼反应和缩合反应制得吗氯贝胺，总收率可达71.；2%25。