Methods 96 patients with focal seizures in refractory epilepsy were randomly divided into groups GBP and Topiramate (TPM).Beside the normal medicaments, GBP or TPM as add-on therapy for certain group.

• 方法96例难治性局灶性发作癫癎患者随机分为两组，在原用药物基础上，GBP组给予GBP添加治疗，托吡酯(TPM)组给予TPM添加治疗；