Many experiments showed that the CTD played a pivotal role in the coupling mechanism that links mRNA transcription with processing by associating with the transcriptional and processing factors.

• 诸多的实验表明,该结构可通过与mRNA加工因子的相互作用而对其加工过程产生直接或间接的影响,在mRNA的转录和加工的偶联过程中具有重要的作用。