It is known that application of adenosine in the LDT nucleus increases sleep in vivo and directly inhibits LDT neurons in vitro by activating postsynaptic adenosine A_1 receptors.

• 应用腺苷至大脑脚被盖背侧核，在活体中可增加睡眠，在实验室中可通过激活突触后膜腺苷A1受体抑制大脑脚被盖背侧核的神经元的活性。