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- Objective: To induce WI-38 cells senescence by tertbutyl-hydroperoxide (t-BHP) and establish a model of premature senescence, to investigate the anti-aging effect of the ginsenoside Rgl on the model of premature senescence induced by t-BHP. 目的:用t-BHP(三丁基过氧化氢,tert-butylhydroperoxide)诱导WI-38细胞衰老,建立体外细胞衰老的模型,并研究人参皂甙Rg1(ginsenoside Rg1)对t-BHP诱导的细胞衰老的保护作用及其可能机制。
- Aim To explore the possible role of p21, cyclin E and cyclin-dependent kinase 2 (CDK2) in the protection of ginsenoside Rgl against tert-butylhydroperoxide (t-BHP)-induced senescence in WI-38 cells. 目的 探讨p21、细胞周期蛋白E(cyclin E)和周期蛋白依赖性蛋白激酶2(cyclin-dependent kinase 2,CDK2)在人参皂苷Rgl对抗三丁基过氧化氢(t-BHP)诱导’WI-38细胞衰老过程中的可能作用。
- p21, cyclin E and CDK2 may be involved in the process of ginsenoside Rgl protection against t-BHP-induced senescence in WI-38 cells. 人参皂苷Rgl对抗三丁基过氧化氢对细胞衰老的诱导作用可能与其改变p21,cyclin E和CDK2的表达水平有关。
- Ginsenoside Rgl 人参皂苷Rg1
- ginsenoside Rgl and Rb1 人参皂甙Rg1
- Analysis on Karyotye of Eremurus Inderiensis (M.B.) Rgl. 粗柄独尾草染色体核型分析
- OBJECTIVE: To study the extraction process of ginsenoside. 目的:研究人参皂苷的提取工艺。
- panax ginsenosides Rgl 人参皂苷Rg1
- Conclusion Ginsenoside can prevent or delay the development of hypertrophy. 结论人参皂苷在早期能预防或延缓心肌肥大的发生。
- The results were as follows:the number of chromosome of Eremurus inderiensis (M.B.) Rgl. 结果表明:粗柄独尾草的染色体数目为2n=14;
- It is possible that their overexpression may play an important role in the ginsenoside biosynthesis. 因而提示,它们可能在人参皂苷生物合成中发挥了重要作用。
- Objective:To explore the Effection of Ginsenoside(GS)on mice G422 Glioma immune function. 目的:探索人参皂苷对小鼠G422胶质瘤免疫功能的影响。
- The survivalrate of BT325 was obviously raised by ginsenoside Rg 1, and the expression of NEP was increased. 人参皂苷Rg1能提高LPS诱导的BT32 5细胞的存活率 ,使细胞内NEP的表达增高。
- As a model terpenoid, the ginsenoside is one of Panax ginseng's main effective components. 人参皂苷是人参的主要有效成分之一,属典型的萜类化合物。
- OBJECTIVE To study the preparation methods for ginsenoside phytosome(GSP) and their pellets coated with HPMC. 目的研究制备人参总皂苷磷脂复合物(GSP)及其包衣微丸的方法。
- In China,ginsenoside Rg3 has been authorized to use in clinic as an new anti-tumor durg in 2001. 我国已于2001年批准人参皂甙Rg3作为一种抗肿瘤新药上市。
- Abstract: As a model terpenoid, the ginsenoside is one of Panax ginseng's main effective components. 摘要: 人参皂苷是人参的主要有效成分之一,属典型的萜类化合物。
- Ginsenoside Rg3 is a drug isolated from ginseng which had been proved to have the effect of anti-tumor . 人参皂甙Rg3(Ginsenoside Rg3)是人参中已被证明具有抗肿瘤疗效的一种皂甙。
- Methods:40 Wistar rats were randomly into normal group,model group and Ginsenoside group. 方法:采用D-半乳糖皮下注射制作衰老模型,共分4组。
- By colorimetry, the adsorptive capacity and service life of D - 101 macro reticular resin for ginsenoside were studied. 用比色法研究了D-101大孔树脂在不同条件下的吸附容量及使用寿命。
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