Conclusion: Staphylococcus aureus and pseudomonas aeruginosa are main pathogenes of chronic suppurative otitis media in Jinan region.Both of them resisted high to penicillin antibiotics.

• 结论：金黄色葡萄球菌和铜绿假单胞菌是济 南地区慢性化脓性中耳炎的主要致病菌，二者对青霉素类抗生素有较高的耐药率。