Conclusion The result of this study indicated that admmistration of exogenous PDTC may attenuate the severity of SAP by inhibiting NF-kB activation and thus induced apoptosis of pancreatic acinus cells.

• NF-kB 的活化显著低于SAP 组(P<0.；01)。 结论 SAP 时；PDTC 可能通过抑制 NF-kB 的活化；从而抑制 NF-kB 介导胰腺细胞的抗凋亡效应；减少胰腺腺泡细胞坏死。