Conclusion The formation of gallstone was related to alteration of bile acid matabolism. lncreasing of CA/CDCA and DCA% may be dangerous signals of gallstone.

• 结论胆结石的形成与胆汁酸代谢紊乱密切相关，CA／CDCA比值及DCA%25升高，可作为胆结石形成的危险信号。