By selecting the proper amphiphilic polymer, stable PEGylated polyplexes were fabricated successfully to improve stability and transfection efficiency at a physiological salt concentration.

• 通过对两亲聚合物中疏水链段的选择调控，可制备稳定的PEG化基因超分子组装体，提高基因传递体系在生理盐溶液中的稳定性及基因转染效率。