By means of quaternion-square regression-rotation orthogonal experimental design, we probed into the effect on the extraction rate by times, water, temperature and time.

• 应用四元二次方程回归旋转正交实验设计，探讨浸提次数，浸提剂倍数，浸提温度和浸提时间对硒多糖浸提率的影响。