As an ideal model for in vitro ES cells differentiation, EBs recapitulate many aspects of the lineage specific differentiation programs and temporal and spatial gene expression patterns of early embryogenesis.

• 作为ES细胞体外分化的理想模型,EBs可以再现胚胎早期发育过程中的谱系特异性分化程序及基因时空表达模式的诸多方面,因此被广泛用于研究胚层间相互诱导、器官空腔化形成等胚胎早期发育事件。