A similar metal cluster is believed to be involved in the oxygen-atom insertion into methane to form methanol by the particulate methane monooxygenase in methanotrophic bacteria.

• 一个类似的铜簇合物可将氧原子嵌入于甲烷分子形成甲醇分子据信是微粒体甲烷单氧化酵素的活性中心。