A growing body of evidence from the animal experiments and clinical trials suggest that 5-hydroxytryptamine (5-HT) and its specific receptors play a key role in the pathophysiological mechanism of IBS.

• 大量的动物实验和临床试验已证实5-羟色胺(5-HT)及其受体参与IBS的病理生理机制,并发挥重要的作用。