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- Objective To immunologically characterize the binding activity of a genetic engineering human antibody against keratin. 目的对1株基因工程人抗角蛋白抗体识别抗原的特性进行鉴定。
- EMSA showed that stimulation of HSC by Aldo markedly increased AP-1 DNA binding activity. Aldo可增强HSC的AP-1的DNA结合活性。
- The autoimmune regulator(AIRE) showned DNA binding activity and transcrip-tional transactivation potential. 自身免疫调节因子(autoimmune regulator,AIRE)是一种具有转录活化潜能的DNA结合蛋白。
- Objective:To study the binding activity of anne xi n B1 to externalized phosphatidylserine. 目的 :研究 annexin B1与磷脂酰丝氨酸的结合活性。
- T 3 decreased the binding activity between IRP and IRE, particularly at concentration of 50 nmol/L. T3 能减少IRP IRE的结合活性 ,且以T3 为 5 0nmol L时减少最为明显。
- In addition, the Jingqianping granule has modulatory effect on the upregulation of the GABAAR binding activity. 中药经前平颗粒可对GABAAR 结合活性含量异常变化起到调节作用。
- The scFv was produced in Escherichia coli and appeared binding activity with BNYVV antigen by ELISA method. 将质粒在大肠杆菌中表达，ELISA法检测出表达产物有与BNYVV抗原结合的活性。
- The autoimmune regulator (AIRE) showned DNA binding activity and transcriptional transactivation potential. 自身免疫调节因子(autoimmune regulator, AIRE)是一种具有转录活化潜能的DNA结合蛋白。
- Thus, the heparin binding activity of JEV may play an important role in its function on cellular surfaces. 因此，细胞表面上的肝素与日本脑炎病毒外套膜蛋白间的作用关系对于病毒进入细胞机制中扮演著重要的角色。
- The successfully prepared anti-keratin Fab with binding activity to human keratin laid a solid foundation for its further application. 获得了具有活性的抗角蛋白的Fab抗体 ,为其应用研究打下了基础 ,也表明包涵体表达基因工程抗体技术是可行的。
- Conclusion Upregulation of GABAAR binding activity in pallium and hypothalamus may be one of the main mechanisms for PMS with liver-qi invasion. 结论 大鼠皮质和海马GABAAR结合活性增加可能是PMS肝气逆证的重要机制之一。
- Binding activity of annexin B1 to externalized phosphatidylserine[J].Di-er Junyi Daxue Xuebao(Acad J Sec Mil Med Univ),2004,25(1):44-46. Annexin B1与磷脂酰丝氨酸的结合活性[J].;第二军医大学学报;2004;25(1):44-46
- Electrophoretic mobility shift assay (EMSA) and competition tests also demonstrated its binding activity to the target element. 体外凝胶电泳阻抑分析及竞争实验亦证明该蛋白质与沉默子DNA存在相互作用。
- Conclusions This result indicate that PCR primer introduced V region N terminal changes may seriously affect the antigen binding activity. 结论在构建小分子抗体时，PCR引物引入的氨基酸残基的改变可影响所表达抗体的活性。
- After the renaturation of antibody Fab, its binding activity was identified by ELISA and antibody competitive inhibitionassay in vitro. 经超声破碎、洗涤、变性和复性后，采用双抗体夹心ELISA法及体外抗体竞争抑制试验鉴定表达产物的生物学活性。
- Anti human BPI polycolonal antibodies or monoclonal antibodies not only increase the bactericidal activity, but also increase the binding activity of porcine BPI to endotoxin. 抗人BPI多抗或单抗不仅能增加猪源BPI的杀菌活性 ,而且能增加其结合内毒素活性
- The binding activity of various CsA analogs was shown as following:CsA>CsC>CsD>CsB.CONCLUSION The cyclophilin A binding assay is sensitive,reproducible and stable. 对几种CsA类似物与CyPA的亲和力进行测定的结果表明 ,其亲和力CsA >CsC >CsD >CsB。
- RESULTS The similarity in binding activity was found in a group of antibodies which have the analogous paratope specificity and sequences of variable regions... 结合特异性相似的抗体其配位特异性相似,而且可变区序列也相似。[结论]抗体可变区分子结构的相似性决定了抗体结合特异性和配位特异性的一致性。
- Compared with the model group, the binding activity of GABAAR was downregulated significantly in the pallium and hippocampus in Jingqianping granule preventing group. 与模型组相比，经前平颗粒组大鼠皮质和海马GABAAR活性均明显下降。
- Either the A(C15S) chain and B(C55S) chain alone or in combination can not exhibit the phospholipase A2 activity or synaptosome binding activity of b-Bgt. 纯化的A（C15S）链与B（C55S）单独或混和测试时均无明显Phospholipase A2 的酵素活性，同时也无法与Synaptosome 结合。
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