and Group CMF(n=24,cyclophosphamide,5-fluorouracil and methotrexate),CTX 600 mg/m~2 iv d1.8,5-FU 12 mg/kg,iv drip,d1-5,MTX 0.4 mg/kg,d1,iv.

• CMF组(n=24)(环磷酰胺联合5-氟尿嘧啶；氨甲喋呤):CTX 600 mg/m2静推d1.；8；5-FU 12 mg/kg；静滴；d1-5；MTX 0