EGB have definite antiplatelet aggregative activity, whether is it also through effecting the activity of platelet PDE to inhibit platelet aggregation? EGB有明确的抗血小板聚集作用,那么,它是否也是通过作用于血小板PDE来抑制血小板聚集的呢?
To study the mechanism of the dysfunction of platelet after coronary artery stent implantation (CASI),we observed the change of the product of nitric oxide (NO),activity of NO synthase (NOS) and L-Arginine transport before and after CASI. 通过观察冠心病人PTCA支架植入术后血小板一氧化氮（NO）生成、NO合酶（NOS）活性和L-精氨酸（L－Arg）转运的变化，探讨PTCA支架术后血小板功能受损的机制。
TNM stage、pathologic type、metastasis of lymph node、bone and viscus as well as surgery has no effect on CD62p expression and activation of platelet. 根据患者体内肿瘤负荷、肿瘤分期、病理类型、是否发生淋巴结、骨及内脏转移的不同进行对比研究。
Conclusion： Depside Salt from Salvia Miltiorrhiza injection can remarkably inhibite the aggregation and activation of platelet，and is definitely effective for angina pectoris. 2． 丹参多酚酸盐能降低血小板聚集率和P-选择素，具有抑制血小板聚集和活化的作用，可作为有效的抗P-选择素和抗血小板药物。
Intravascular platelet activation showed a dynamic change before and after PCI, and activation of platelet was positively related to stability of plaque and periprocedural myocardial damage. 结论：血小板激活状态与斑块稳定性密切相关，血小板活性在PCI前后有动态改变，与PCI术后心肌损伤相关。