. An in vivo model simulating physiologic levels of glycosaminoglycan loss was created to aid in understanding the relationships between altered biochemistry, altered mechanics, and altered cellular function in degeneration.

• 我们创造一种氨基葡聚糖含量降低到生理水平的体内模型，目的是为了了解椎间盘生化改变、力学改变和退变椎间盘细胞功能改变之间的相互关系。