Using radioimmunoassay and Dot Blot, we have studied the effects of hypoxia on the expression of COX and TxS genes and on the production of PGI2 and TXA2 in cultured coronary artery endothelialcells (CAEC)and smooth muscle cells (CASMC).

• 用放免及斑点杂交法研究缺氧对培养的冠状动脉内皮细胞（CAEC）和平滑肌细胞（CASMC）的环氧合酶（COX）和血栓素A2合成酶（TxS）基因表达的影响。 实验表明在缺氧时，CAEC和CASMC中COX-1表达增加，总光密度比常氧对照组分别高3倍和1.；8倍；