Using polyethylene glycol(PEG) as internal reference, electrospray ionization(ESI)/time - of -flight mass spectrometry(TOF - MS) was developed to determine the accurate mass of the protonated molecular ions of five erythromycin analogue antibiotics.

• 研究了聚乙二醇(PEG)为内标物的电喷雾(ESI)/飞行时间质谱(TOF-MS)准确质量测定方法；并应用于5个红霉素类抗生素质子化分子离子(MH~+)的质量测定.