Triple promoter mutations at nucleotides 1762-1764-1896 prevailed in non-responders (60%) as compared to responders (20%).L180M/M204V mutations were identified during virological breakthrough.

• 60%25非应答者核苷酸1762-1764-1896的三重启动子发生突变，相比之下，应答者仅20%25发生突变。