Treatment recommendations include simplifying the pain regimen, avoiding polypharmacy with its risk of drug interactions, and beginning drugs at lower dosages and titrating upward as needed.

• 推荐的治疗方法包括给以单一的止痛药物，避免给予多种混合药物以避免药物的互相影响，从低剂量开始给药并根据需要一点一点的增加用量。