To detect the variability and its pathogenecity of Helicobacter pylori(H.pylori),fifty- two biopsy specimens and 18 strains of H.pylori were performed PCR for 16S rRNA gene and flagellin A gene(flaA). PCR-RFLP and PCR-RFLP-SSCP were also performed.

• 我们对52例胃粘膜活检标本和18株 Hp 临床分离株进行 Hp 特异的16S rRNA 基因和鞭毛素 A 基因 PCR 扩增和 PCR-RFLP 及 PCR-RFLP-SSCP 分析,以检测 Hp 鞭毛素 A 基因的变异性,进而研究其与 Hp 致病性的关系。