This study was aimed to investigate the expression and regulation mechanism of DNA-dependent protein kinase catalylic subunit (DNA-PKcs) in chronic myeloid leukemia (CML) and its role in blast crisis of CML.

• 本研究旨在探讨髓系粒细胞白血病(CML)的DNA依赖蛋白激酶催化亚基(DNA-PKcs)基因表达水平、调控机制及其在CML急性变中的作用。