This study indicates that CpG-ODN can enhance the humoral immunity to Ag in chickens, but short-strand CpG-DNA has no significant stimulation and long-strand P-CpG-DNA containg high frequence CpG motifs can inhibite immune response.

• 本研究表明，CpG-ODN能增强家禽的免疫系统对抗原的体液免疫应答，短链CpG-DNA没有明显的增强功能，而CpG基序含量高的长链CpG-DNA反而有抑制作用。