This review presented several new tools used in the nonclinical studies of the safety e-valuation, including biomarkers, toxicogenomics, toxicoproteomics, metabonomies, and systems toxicology.

• 现综述国外遗几年在非临床安全性评价中采用的新工具,包括生物标记物,以及毒理基因组学、毒理蛋白质组学、代谢组学和系统毒理学方面的新技术。