This review highlights the mechanisms that at present are known to be involved in the oocytes maturation and factors for IVM, and the significance of IVM clinical application is anticipated.

• 文章对人卵母细胞体外成熟的机理、影响卵母细胞体外成熟的因素进行了综述，最后对卵母细胞体外成熟的临床意义进行了展望。