This paper summarizes the elements of the nucleic acid vaccine, the preparation, the method and mode of inoculability, the effect of immunity and the securiy of vaccine in fish.

• 就核酸疫苗的作用机理、鱼用核酸疫苗的构建、接种的方法和途径、免疫效果以及安全性问题的研究作了概括。