This paper reviews the definition, action mechanism of antisense nucleic acid, as well as its application and researches progress in fighting virus, preventing and curing cancer, cell languishment, signal mechanism, nerve center system and ophthalmology.

• 综述了反义核酸技术的作用机理及其在抗病毒、抗肿瘤、细胞凋亡、信号机制、中枢神经系统以及眼科等方面的运用以及研究进展。