These results indicate that HSR could induce novel synthesis of HSP70,which could pro-tect BPAECs against H_2O_2 injury through increasing BPAECs endogenous antioxidative activity.

• 放线菌酮可阻断热处理诱导的PBAECs70－KD热休克蛋白的合成，消除其保护作用。