These findings suggest that subcellular distribution and phosphorylation state of GluR1S831 in parvalbumin-positive interneurons may play a significant role in the pathogenesis of dyskinesia in PD with chronic 1-dopa treatment.

• 纹状体小清蛋白阳性中间神经元上GluR1及GluR1Ser831磷酸化的改变,可能与PD异动症的发生有关。