Therefore, newer immunosuppressive agents such as mycophenolate mofetil and sirolimus (Rapa) have raised the possibility of withdrawing or avoiding CNIs altogether.

• 因此，新的免疫抑制剂如：麦考酚酸吗乙酯和西罗莫司（雷帕霉素）的使用使CNI撤退或避免其使用的可行性上升。