Then,2-methyl-2-hydroxy-1-phenyl-1-pentanone was prepared by chlorination and hydrolysis with 2-methyl-1-phenyl-1-pentanone in the presence of NaOH and CCl4 as chlorinating agent and tetrabutyl ammonium bromide as the phase transfer catalyst.

• 最后在氢氧化钠水溶液中,以四氯化碳为氯化试剂,四丁基溴化铵作相转移催化剂,2-甲基-1-苯基-1-戊酮直接氯代和水解制得2-甲基-2-羟基-1-苯基-1-戊酮。