The transdermal delivery of piroxicam was pronouncelly improved by enhancing the solubility of piroxicam with Tween 80 and forming LTRs by electroporation.

• 综合利用聚山梨酯80的促渗作用和电致孔时形成的水性通道,可以有效提高吡罗昔康的透皮量。